It would definitively affect marketability although it depends. Note of Death is kind of okay but Killer Book would have hurt sales I think. There's a detective american tv show called Murder She Wrote (because the detective write murder novels) so it could be funny if Death Note was called Murder He Wrote because it just sounds goofy. But some titles sounds so good I like pronouncing it for no reason sometimes. Ghost in the Shell is one of those. I think the fact that it was ahead of its time and the animation would still have made it famous regardless of its title. Come to think of it, Rurouni Kenshin has the alternative name Samurai X but I don't know why they changed the name or if it had an effect on its marketability. Personally I would just have translated it to Kenshin the Wanderer. It's also weird because the main character isn't a samurai at all and never has been, and doesn't follow bushido. It sounded stylish I guess. Gunnm is also Battle Angel Alita I think? But I barely know anything about Gunnm so I don't really have an opinion on the matter.

Caucasians outside of Europe. You know, for balance.