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Known for its Space Western theme, Trigun is about a man named "Vash the Stampede" and the two Bernardelli Insurance Society employees who follow him around in order to minimize the damages inevitably caused by his appearance. Most of the damage attributed to Vash is actually caused by bounty hunters in pursuit of the "60,000,000,000$$" (sixty billion "double dollars") bounty on Vash's head for the destruction of the city of July.

YuYu Hakusho follows Yusuke Urameshi, a street-brawling delinquent who, in an uncharacteristic act of altruism, is hit by a car and killed in an attempt to save a young boy by pushing him out of the way. His ghost is greeted by Botan, a woman who introduces herself as the pilot of the River Styx, who ferries souls to the Underworld where they may be judged for the afterlife.

Trigun: Badlands Rumble is a 2010 film by Madhouse. It is based on the Trigun manga, written by Yasuhiro Nightow.

The students of class 3-E have a mission: kill their teacher before graduation. He has already destroyed the moon, and has promised to destroy the Earth if he can not be killed within a year.