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Rintaro Okabe is a self-proclaimed "mad scientist" who believes that an international scientific organization named SERN is conspiring to reshape the world according to its own interests. He and his friend Itaru Hashida inadvertently create a gadget able to send messages to the past.

The eccentric, self-proclaimed mad scientist Rintarou Okabe has become a shell of his former self. Depressed and traumatized after failing to rescue his friend Makise Kurisu, he has decided to forsake his mad scientist alter ego and live as an ordinary college student.

Case Closed, also known as Meitantei Conan (Detective Conan), is a Japanese detective manga series written and illustrated by Gosho Aoyama and is serialized in Weekly Shonen Sunday since 1994. The name "Case Closed" for the English language release results from "unspecified legal considerations" of the name Detective Conan.

On June 1983, Keiichi Maebara moves with his family to Hinamizawa, a peaceful rural village. He quickly befriends his new schoolmates Rena Ryugu, Mion Sonozaki, Satoko Hojo, and Rika Furude, usually spending their leisure time playing board games.

One morning, as office worker Kobayashi gets ready for another day at work, she is greeted by a terrifying sight—the head of a large dragon staring into her eyes from across the balcony. The dragon immediately transforms into a cute, busty and energetic young girl in a maid outfit, who introduces herself as Tohru.

The story is set in Heavenly Host Elementary School, an elementary school that was torn down following the murders and disappearances of several of its staff and students. By the start of the story, another school called Kisaragi Academy has been built over the elementary school site.