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After losing their mother, Alphonse and Edward Elric attempt to bring her back using the forbidden science of human alchemy. However, alchemy operates on the theory of equivalent trade, and breaking the human alchemy taboo carries a heavy price.

Fullmetal Alchemist: Brotherhood, commonly referred to as FMAB is the second adaptation of the hit manga series Fullmetal Alchemist by Hiromu Arakawa. In 2003, shortly after the manga began its run, the first adaptation titled Fullmetal Alchemist was made.

A fugitive alchemist with mysterious abilities leads the Elric brothers to a distant valley of slums inhabited by the Milos, a proud people struggling against bureaucratic exploitation. Ed and Al quickly find themselves in the middle of a rising rebellion, as the exiled Milos lash out against their oppressors.

The brothers Elric will consider the answers that are left once the Philosopher's Stone has guided their saga to and end. True sacrifice, the deep love of family, the cruel truths of life and death.

The extra episode is based on a side story of "Fullmetal Alchemist" manga published in "Fullmetal Alchemist Perfect Guidebook" (2003). Edward and Alphonse meet a blind alchemist named Jude who supposedly performed a successful human transmutation, resurrecting a young girl named Rosalie Harbinger.

Saotome Ranma, a teenage martial artist, and his father Genma travel to the 'cursed training ground' of Jusenkyo in China. There, despite the warnings of the Chinese guard, they fall into the cursed springs.

Nineteen-year-old college student Hana meets a young man who sneaks into her classes for lessons and falls in love with him immediately. They soon start dating.

A side story of Darker than BLACK, also known as Episode 26. A Contractor was killed and it was rumored that his corpse and possessions were buried under a Sakura tree.

Makoto Ito rides the train to and from school every day. However, at the beginning of his second term, he falls in love with a beautiful girl that also rides the train.