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Gurren Lagann takes place in a fictional future where Earth is ruled by the Spiral King, Lordgenome, who forces mankind to live in isolated subterranean villages. These villages have no contact with the surface world or other villages, and are under constant threat of earthquakes.

The world is beginning to get back on it's feet and rebuild after the destruction that lied in Sephiroth's wake. Not all is going well, however, as a new disease known as Geostigma threatens the world.

While loosely based on the French novel Le Comte de Monte-Cristo, the story takes place on the far future, during the 51st century, year 5053. Although it retained some elements from 19th century France, the show is mostly dominated by futuristic concepts.

Fullmetal Alchemist: Brotherhood, commonly referred to as FMAB is the second adaptation of the hit manga series Fullmetal Alchemist by Hiromu Arakawa. In 2003, shortly after the manga began its run, the first adaptation titled Fullmetal Alchemist was made.

On his first day at his new school, twelve-year-old Ritsuka Aoyagi meets a mysterious twenty-year-old male named Soubi Agatsuma. Soubi claims to be a good friend of Ritsuka's brother, Seimei, who was murdered when Ritsuka was ten years old.