HoneyMew

known as 'magical doremi' in the states, this series spanned 4 seasons (5 counting the ova) and two movies

The story revolves around Rin Okumura, a teenager possessing abnormal strength and endurance who, along with his younger twin brother Yukio, was raised by Father Shiro Fujimoto. Soon after Yukio departs to study at the prestigious True Cross Academy, Rin learns that he is the son of Satan, the strongest of all demons.

When his adopted father, Shiro Fujimoto was killed by his biological father, Satan, Rin Okumura swore to become an exorcist to avenge Shiro's death declaring war on his own blood-relatives of the underworld…Everyone is in the midst of preparing for a festival which is celebrated once every 11 years in True Cross Academy Town. However behind the scenes in the shadows, a "Phantom Train" goes berserk while the barriers protecting the town from demon intrusions were under repair.

Yuki Cross earliest memory is of being attacked by an insane "Level E" type vampire and saved by Kaname Kuran, a pureblood vampire for whom Yuki tries to deal with her seemingly unobtainable love for her hero. Ten years later, Yuki, along with her childhood friend, Zero Kiryu are school guardians at Cross Academy where her adoptive father, Kaien Cross is the headmaster.

Yuki's earliest memory is of a stormy night in winter, wherein she was attacked by a vampire..

Cross Academy is different from any other school. It has a Day Class and a Night Class, with different uniforms and no interaction between these two classes.