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After a traffic accident, Kazuma Sato’s disappointingly brief life was supposed to be over, but he wakes up to see a beautiful girl before him. She claims to be a goddess, Aqua, and asks if he would like to go to another world and bring only one thing with him.

Yukiteru Amano (or Yuki) is a loner who never really interact with people and prefers writing a diary on his cell phone with his only companion being an imaginary friend named Deus Ex Machina, the God of Time and Space. However, Yuki soon learns that Deus is not a figment of his imagination but real when Deus makes him a participant in a battle royale with eleven others.

The story follows Kaizaki Arata, a 27-year-old jobless man, who fails at every job interview he had after quitting his last company. His life changes after he met Yoake Ryou of the ReLife Research Institute, who offered him a drug that can change his appearance to 17-years-old and to become a subject in an experiment for one year.

The suspense horror/dark fantasy story is set in Tokyo, which is haunted by mysterious "ghouls" who are devouring humans. People are gripped by the fear of these ghouls whose identities are masked in mystery.