Csyrian

They say that you'll never know what a person's real character is until you've started living with him/her/ them under one roof. Well, it definitely is true in the case of a 16 year old female protagonist, Tohru Honda from the series, Fruits Basket.

Based on the novel, "D - Demon Deathchase", by Hideyuki Kikuchi. 2000.

Hellsing, a secret organization within the British government, has long been battling supernatural threats to keep people safe from creatures of the night. They have a secret weapon in the form of an incredibly powerful vampire Alucard.

Attack on Titan (literally translated as "Advancing Giants") is a Japanese manga series, and now an anime, originally written and illustrated by Hajime Isayama. The story centers around the lives of Eren Yeager, his adoptive sister Mikasa Ackerman, and their friend Armin Arlert, who live in a world where the remnants of the human population live inside cities surrounded by enormous walls due to the sudden appearance of the Titans, gigantic humanoid creatures who devour humans seemingly without reason.

Tohru Honda is 16 year old orphaned girl who gets invited to live in the house of her classmate, the handsome boy Sohma Yuki, and his cousins, 16 year old Kyo and 27 year old Shigure. However, these young men and parts of the rest of their family (both close and distant) hold a curse; if they are hugged by the opposite gender, they transform into animals of the Chinese Zodiac.

The story of Death Note revolves around a high school student called Yagami Light. His life changed when he saw a supernatural notebook that fell from the sky.

Haruhi Fujioka is searching for nothing more than a quiet place to study in the most elite high school academy in all of Japan when she stumbles across the mysterious third music room. Inside she encounters six beautiful men, the members of the host club.